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RayCure SPE series provides high-quality SPE cartridges for various types of solid phase extraction, including manifold, vacuum as well as automated solid phase extraction equipment, well compatible with RayKol automated solid-phase extraction systems. RayCure SPE cartridges utilize high-quality sorbents to ensure the efficiency of SPE clean up, offers full range of solid phase extraction cartridges for various sample matices. Strict quality managment and control ensures high recovery rate of analytes and experiment reproducibility. RayKol provides effective, efficient and economial cartridge SPE with high performance.

SPE CARTRIDGE TYPES

RayCure SPE Columns

RayCure SPE series provide pre-packed SPE columns with a variety of sorbents, resins and cartridge size for various methods and target analytes.

RULES TO SELECT RAYCURE SPE CARTRIDGE TYPES

Rule I:

The properties of solid phase packing in SPE cartridges should be match to target compounds.

Rule II:

Take the advantage of differences between analytes of interest and interferences

Rule III:

Consider nature of SPE sample matrices, characteristics of analytes and solubility of used solvents

Users can select RayCure SPE columns depending on properties of desired analytes and sample matrices as following selection guides.

Target compounds Properties of analytes Corresponding SPE

Solubility Polarity/Ionicity SPE mechanism Sorbent phase

Water soluble Compounds with high/low polarity Non-polar C18

Polymer HLB

Ionic compounds Anion exchange MCX, WCX

Cation exchange MAX, WAX

Soluble in organic solvents Polar compounds Normal phase bonding PSA, NH2

Compounds with neutral polarity Normal phase adsorption Silica, Florisil

Non-polar compounds Reversed phase C18

Based on nature of SPE sample matrices

SPE sample matrices

SPE sample matrices Target compounds Impurities RayCure SPE column

Fruits, vegetables, fruit juice, vegetable juice, fruit wine, herbs Multiple pesticide residues Carbohydrates, pigments, organic acid, phenol RayCure QuEChERS d-SPE kits

RayCure NH2

RayCure PSA

RayCure GCB/NH2

RayCure GCB/PSA

RayCure Florisil

Weak polar pesticides Carbohydrates, pigments, organic acid, phenol RayCure HLB

RayCure C18

Alkali pesticides Carbohydrates, pigments, organic acid, phenol RayCure MCX

RayCure WCX

Acidic pesticides Carbohydrates, pigments, organic acid, phenol RayCure MAX

RayCure WAX

Dairy products, blood, urine, animal tissues Neutral, weak alkali, weak acidic drugs Proteins, fats RayCure HLB

RayCure C18

Alkali drugs Proteins, fats RayCure MCX

RayCure WCX

Acidic drugs Proteins, fats RayCure MAX

RayCure WAX

Soil, wastewater hydrophobic organic pollutants Humic substances RayCure HLB

RayCure C18

Pesticide residues Humic substances RayCure Florisil

Oil and grease Fat-soluble vitamins, phospholipids, aflatoxins Fats RayCure Silica

RayCure NH2

RayCure PSA

HOW DOES SPE COLUMN WORK?

SPE is a conventional and efficient extraction technique, it uses the affinity of solutes dissolved or suspended in mobile phase for stationary phase to separate desired compounds from a mixture. And there are two solid phase extraction mechanisms to obtain target analytes from complex samples, to retain desired compounds in stationary phase or retain impurities in solid phase. Depending on the difference of two mechanisms, SPE procedures could be a bit various.

When sample portion passes through SPE column, undesired impurities are discarded with mobile phase, target compounds are retained in stationary phase, then rinse stationary phase with eluents to collect target compounds. It is the most commonly used purification mechanism of solid phase extraction.

In the opposite, to retain impurities in stationary phase, target compounds and few impurities are collected in mobile phase when sample portion passes through SPE column. Rinse the stationary phase which impurities is retained with solvents to obtain rest of retained target compounds. This mechanism is mostly used to eliminate fat-soluble impurities of ion analysis and analysis of multiple pesticides in fruits and vegetables.

Raykol Group is a leading professional supplier focusing on R&D, design and manufacture for automated laboratory equipment and solutions in the laboratory automation systems market. And we provide pre-sales product selection guide and after-sales technical supports. RayKol's lab automation systems and products are applied to sample preparation process in the area of food safety, environmental science, agriculture, pharmaceuticals and life science.