| Model: | 注射级 |
|---|---|
| Brand: | zhonghuan zhongjie |
| Origin: | Made In China |
| Category: | Chemicals / Pharmaceutical Chemicals |
| Label: | Cyclodextrin , Remdesivir |
| Price: |
US $600
/ pc
|
| Min. Order: | 1 pc |
| Last Online:21 Mar, 2025 |
[Sodium sulfobutyl betacyclodextrin] Basic information:
Product Name: Sodium sulfobutyl betacyclodextrin
Quality standards: USP-NF2023、EP10.3、 Enterprise standards
Appearance: White powder
CAS NO.：182410-00-0
Molecular formula: C42H70-nO35 (C4H8SO3Na) n, where n represents the degree of substitution
Molecular weight: 1134+158n
[Sodium sulfobutyl betacyclodextrin] Product features (Usage description):
Sodium sulfobutyl betacyclodextrin, also known as sulfobutyl ether betacyclodextrin sodium salt, is a sodium salt of betacyclodextrin alkylated by 1,4-butanesulfonic acid lactone under alkaline conditions. It is an anionic highly water-soluble cyclodextrin derivative that can form non covalent complexes with drug molecules, thereby improving drug stability, water solubility, safety, reducing nephrotoxicity, alleviating drug hemolysis, controlling drug release rate, masking adverse odors, etc.
【 Route of administration 】: Injection, oral administration, nasal administration, ocular administration, with special affinity and inclusion properties for nitrogen-containing drugs.
[Sodium sulfobutyl betacyclodextrin] Product performance:
1. Solubilization:
Neutral, positive, and negative active ingredients can effectively bind with sulfobutyl betacyclodextrin, increasing the solubility of compounds with different solubilities in the active ingredient solution by 10 to 25000 times.
2. Convenient drug administration:
Sulfobutyl betacyclodextrin has good biocompatibility and can be administered by injection, oral, ocular, nasal, topical, and inhalation.
3. Good security:
Normally, it can be quickly and completely eliminated from the kidneys after administration. Safe data has been provided in vitro experiments and in vivo acute, subacute, and chronic toxicity studies, and approved for use in human drug formulations.
4. Good stability:
The interaction with sulfobutyl betacyclodextrin provides a beneficial protective environment for the active pharmaceutical ingredient in its lipophilic cavity, while the hydrophilic surface provides excellent water solubility, solubility, and stability.
