Model: | lingding461 |
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Brand: | lingding |
Origin: | Made In China |
Category: | Chemicals / Organic Chemical Materials / Pharmaceutical Chemicals |
Label: | anesthesia , Pharmaceutical raw m , Chemical raw materia |
Price: |
US $88
/ kg
|
Min. Order: | 1 kg |
Live Chat: | Last Online:13 Mar, 2023 |
Product name: Procaine
CAS:59-46-1
Molecular formula :C13H20N2O2
Molecular weight :236.31
EINECS No. :200-426-9
Physical property
Melting point :61°
Boiling point :378.78°C(roughestimate)
Density :1.0604(roughestimate)
Refractive index :1.5430(estimate)
Storage conditions: Keepindarkplace, Sealedindry RoomTemperature
Solubility: DMSO (Slightly), MeChemicalbookthanol (Slightly)
Form :Solid
Acidity coefficient :(pKa)pKa9.04±0.01(H2O,t=25,I=0.1(NaCl))(Approximate)
Color :WhitetoOff-White
Water solubility :9.45g/L(30ºC)Merck14,7757
Stability :Hygroscopic
1.Procaine is a local anesthetic with a para-amino function. Sensitization mainly concerns medical, dental and veterinary professions.
2.Procaine is mainly used in dental or medical procedures requiring infiltration anesthesia, peripheral block, or spinal block.
3.Procaine is very quickly metabolizedin the plasma by cholinesterases and in the liver via ester hydrolysisby a pseudocholinesterase. The in vitroelimination half-life is approximately 60 seconds. Any conditionthat decreases the cholinesterase concentration may increaseexposure to procaine and potential toxicity. Decreasedenzyme activity can be found with genetic deficiency, liverdisease, malignancy, malnutrition, renal failure, burns, thirdtrimester of pregnancy, and following cardiopulmonary bypasssurgery. Ester hydrolysis produces PABA, the compoundresponsible for the allergic reactions common to theester anesthetics. Procaine is not used topically because of itsinability to pass through lipid membranes and finds use as aninfiltration agent for cutaneous or mucous membranes, forshort procedures. Procaine is also used for peripheral nerveblock and as an epidural agent to diagnose pain syndromes.
WhatsApp: + 8617367778264
Email:andy@hbldbiotech.com
Sincerely Andy
Payment Terms: | TT |
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