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The 2019-NCoV is a large family of viruses known to cause colds as well as more serious illnesses such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). The novel coronavirus is a novel coronavirus strain that has never been found in humans before.

In more severe cases, the infection can lead to pneumonia, severe acute respiratory syndrome, kidney failure, and even death.

FRENOVO COVID-19 IgG/IgM rapid test (Whole Blood/ Serum/ Plasma) is a rapid test that utilizes a combination of COVID-19 antigen-coated colored particles for the qualitative detection of IgG and IgM antibodies to COVID-19 in human whole blood, serum, or plasma as an aid in the diagnosis of primary and secondary COVID-19 infections.

Background of COVID-19 IgG/IGM Test

The 2019-NCoV is a large family of viruses known to cause colds as well as more serious illnesses such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). Novel coronavirus is a novel coronavirus strain that has never been found in humans before.

In more severe cases, infection can lead to pneumonia, severe acute respiratory syndrome, kidney failure and even death.

FRENOVO COVID-19 IgG/IgM rapid test (Whole Blood/ Serum/ Plasma) is a rapid test that utilizes a combination of COVID-19 antigen coated colored particles for the qualitative detection of IgG and IgM antibodies to COVID-19 in human whole blood, serum, or plasma as an aid in the diagnosis of primary and secondary COVID-19 infections.

Principle of COVID-19 IgG/IGM Test

The COVID-19 IgG-IgM Rapid Test (Whole Blood/Serum/Plasma) is a qualitative membrane-based immunoassay for the detection of IgG and IgM antibodies to 2019-nCoV in whole blood, serum or plasma specimen. This test consists of two components, an IgG component and an IgM component. In the IgG component, anti-human IgG is coated in IgG test line region. During testing, the specimen reacts with 2019-nCoV antigen-coated particles in the test cassette. The mixture then migrates upward on the membrane chromatographically by capillary action and reacts with the anti-human IgG in IgG test line region, if the specimen contains IgG antibodies to 2019-nCoV.

A colored line will appear in IgG test line region as a result of this. Similarly, anti-human IgM is coated in IgM test line region and if specimen contains IgM antibodies to 2019-nCoV, the conjugate-specimen complex reacts with anti-human IgM. A colored line appears in IgM test line region as a result.

Therefore, if the specimen contains 2019-nCoV IgG antibodies, a colored line will appear in IgG test line region. If the specimen contains 2019-nCoV IgM antibodies, a colored line will appear in IgM test line region. If the specimen does not contain 2019-nCoV antibodies, no colored line will appear in either of the test line regions, indicating a negative result. To serve as a procedural control, a colored line will always appear in the control line region, indicating that the proper volume of specimen has been added and membrane wicking has occurred.

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