| Model: | pharmaceutical |
|---|---|
| Brand: | - |
| Origin: | - |
| Category: | Chemicals / Pharmaceutical Chemicals |
| Label: | china HPMC , HPME for pharmace , Hydroxy propyl methy |
| Price: |
-
|
| Min. Order: | - |
| Live Chat: | Last Online:14 Nov, 2013 |
|
Common Name |
Hydroxypropyl Methylcellulose |
|
Abbreviation |
HPMC |
|
9004-65-3 |
9004-34-6 |
|
Approval certificate |
Lu Yao Zhun Zi F2012001 |
|
Conforming Standard |
CP (Chinese Pharmacopoeia) USP (United States Pharmacopoeia) EP (European Pharmacopoeia)
|
The product is nonionic cellulose ether, white powder in appearance, odorless and tasteless. It is soluble in water and most polar organic solvents, and sells into transparent or slightly turbid colloidal solution in cold water. The aqueous solution possesses such characteristics as surface activity, high transparency and stable performance. It also owns the property of thermal gelling, thus its aqueous solution can form into glue to separate out after heating, and then it dissolve after cooling, with different gelling temperature in different specifications of products. The solubility changes with viscosity. The lower viscosity is, the larger solubility is. The properties of HMPC of different specifications are different, while solution of HPMC in water will not be affected by PH value.
2、Product Application
In oral preparation, HPMC is mainly applied as tablet adhesive, film coating material and framework material of sustained-release; in topical preparation, it is mainly applied as suspending agent and thickener of ophthalmology preparation, and also as emulsifier, suspensions and stabilizer of gel and ointment.
3.Technical Index
|
Item |
Specification |
||
|
60GD（2910） |
65GD(2906) |
75GD(2208) |
|
|
Methoxy group% |
28.0-32.0 |
27.0-30.0 |
19.0-24.0 |
|
Hydroxypropyl group% |
7.0-12.0 |
4.0-7.5 |
4.0-12.0 |
|
Gelation temperature℃ |
56-64 |
62.0-68.0 |
70.0-90.0 |
|
Viscositympa·s |
3,5,6,15,50,4000 |
50,4000 |
100,4000,15000,100000 |
|
Loss on drying% |
≤5.0 |
||
|
Residue on ignition% |
≤1.5 |
||
|
pH |
4.0-8.0 |
||
|
Heavy Metal |
≤20 |
||
|
Arsenic (As) |
≤2.0 |
||
Explanation:
1. The viscosity in USP is 80%-120% when the marked viscosity equals to or is lower than 100mpa•s, while 75%-140% when the marked viscosity exceeds 100mpa•s.
2. The viscosity in EP is 80%-120% when the marked viscosity is lower than 600mpa•s, while 75%-140% when the marked viscosity equals to or exceeds 600mpa•s.
4. Description of Product
[Storage] Keep dry, keep away from heat and sunshine, and store in closed container.
[Package] Packed in fiber can lined with double layer polyethylene bad.
[Net Weight] 25kg/piece
| Payment Terms: | L/C ,T/T |
|---|---|
