Multi-layer tower extract -- huperzine a latest research shows that: huperzine a is a reversible acetylcholinesterase inhibitor, with high selectivity and low toxicity of multi-layer tower extract pesticide effect time is long, etc, and is by far the more ideal candidate drugs to treat alzheimer's
[product name] multi-layer tower extract (CAS No. : 102518-79-6)
"English name" Huperzia Serrate P.E.
[Latin name] Huperzia serratum
【 plant source 】 Shi Sha Shi Sha genera plants snake Shi Sha
【 appearance 】 brown to white powder
[active ingredients] huperzine a
【 specification 】 1% - 98%
【 molecular weight 】 242.32
【 molecular formula 】 C15H18N2O
【 】 melting point 230 ℃ rotation: 150.4 °
【 solubility soluble in chloroform, soluble in methanol, ethanol, slightly soluble in water
【 method 】 HPLC
[process] the raw material to ethanol extraction, enrichment - extract - solvent extraction to extract - concentrated extract - spray drying, crushing, mixing, packaging and product
Huperzine a is a reversible acetylcholinesterase inhibitor, with high selectivity and low toxicity of multi-layer tower extract pesticide effect time is long, etc, and is by far the more ideal candidate drugs to treat alzheimer's. For myasthenia gravis, age-related memory loss and alzheimer's disease, youth learning disorders and enhance memory.
Pharmacological effects: multi-layer tower extract by Shi Sha plants multi-layer tower [Huperzinaserrata (Thumb) Trev] to extract a kind of alkaloid, is a potent cholinesterase reversible inhibitor, its function characteristics and neostigmine are similar, but their role maintaining time for longer than the latter. Animal experiments showed that this product is selective for true cholinesterase inhibition, the strength of the pseudo cholinesterase inhibition thousands of times; Inhibition method for hybrid of competitive and non-competitive inhibition, and simple competitive inhibitors have significantly different; Thousand layer extracts easy through the blood brain barrier into the central tower, and has the central and peripheral therapy effect; Effective time is long; Absorbed from the gastrointestinal tract is good; Security index; Stability is good. Reversible AChE inhibitors is a kind of powerful, can improve age-related memory loss, can significantly improve memory, cognitive and behavioral function in patients with AD, no obvious adverse reaction, the treatment of alzheimer's disease is one promising drugs
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