Tiamulin can be used as a feed additive for animals in feed and husbandry industries. It could promote the growth of livestock and poultry, and improve feed conversion rate, early pig slaughter time, increase egg laying rate, promoting broiler weight gain. Classfied as one type of antibiotic medicine for swines and poulty, Tiamulin Hydrogen Fumarate (short for Tiamulin) is also one kind of pharmaceutical raw material for animals. It is used for treating fowl chronic respiratory tract disease, pig mycoplasma pneumonia and hemophius pleura pneumonia, and can also be used for dysentery caused by pig treponema.
1, Applied to Swine Industry: Tiamulin is used to prevent and treat mycoplasma infections, Escherichia coli, Salmonella and other diseases caused by Spirochetes of swine Mycoplasma Pneumonia, Haemophilus Pleuro Pneumonia, Endemic Pneumonia (breathing disease) and Swine Dysentery with special effects. Meanwhile, it also cure of Mycoplasma Arthritis, Defense Bacillus Pleuropneumonia, Ileitis, Colitis, Edema and other diseases with good effect.
2, Applied to poultry industry: Loss of mycoplasma on the poultry industry is mainly to reduce egg production, hatching reduced chick mortality levels and reduced weight gain. Control of mycoplasma diseases, the key is to prevent the spread of pathogens through the breeder. Accordingly, Tiamulin can ensure effective control of Mycoplasma gallisepticum and Mycoplasma synoviae. Moreover, it possesses following features:
- A powerful anti-bacterial Pharm Raw Material
- Efficacy remarkable
- High security
- Resistance to low
- With significant economic benefits
II. Charateristics of Product
Tiamulin shows up in white or almost white crystalline powder, soluble in methanol and ethanol, dissolved in water, melting point 143-149 ℃.
-Molecular Formula: C28H47NO4S·C4H4O4,
-Molecular Weight at 609.8.
-CAS: 55297-96-6
-Pharmacopoeia: USP30 complied
III. Specifications
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Appearance
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White crystal powder
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Solubility
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Soluble in water, ethanol and methanol
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Loss on Drying
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Not more than 0.5%
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pH
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3.1~4.1
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Residus on Ignition
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Not more than 0.1%
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Heavy Metal (PPM)
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Not more than 10
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Content of Fumarate
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83.7~87.3%
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Optical Rotation
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+24~+28°
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Melting Point
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Assay (HPLC)
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98.0~102.0%
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Impurities (Total)
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Not more than 2.0%
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Solvent Residue
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Not more than 0.5%
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Absorptivity (400nm)
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≤0.150
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Absorptivity (650nm)
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≤0.030
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IV. Precaution and Handling
There is no known effect from chronic exposure to this product. Repeated or prolonged exposure is not known to aggravate medical condition. However, product dust may cause sneezing, skin irritation or antibiotic sensitivities in some individuals.
Handling of this product should be in accordance with good industrial hygiene and saftey practice. While someone exposes his hands, eyes and nose to the dust of the product, uniform, rubber gloves, safty glasses and dust masks or gas respirators are neccessroy.
V. Storage and Package
This product should be kept under conditions cool, dry and low temperature ( no higher than 30℃). Direct sunlight, moisture and high humidity should be avoided. For preventing poisoning, the product should be kept away from food and water. Combustible materials and strong oxidizing agents also should be kept from the product.
Tiamulin is packed in cardboard drums containing 25kg each.
1) Package Material: Cardborad Drum
External: High-pressure-proof cardboard
Internal: Double static-free plastic bag
2) Package Drum Size
Diameter: 40cm
Height: 60cm
3) Package Weight:
Net Weight: 25Kg/Drum
Gross Weight: 28Kg/Drum
