Home > Products > Chemicals > Pharmaceutical Chemicals

Product Name：6-methyl-2-thioxo-1H-pyrimidin-4-one

Synonyms：2-Mercapto-4-methyl-6-hydroxypyrimidine; 4(1H)-pyrimidinone, 2,3-dihydro-6-methyl-2-thioxo-; 6-methyl-2-sulfanylpyrimidin-4-ol; 6-Methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 6-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-on; 6-Methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine; Methiure; 6-Methyl-2-thiouracil; 4-Hydroxy-2-mercapto-6-methylpyrimidine; 4-Methyl-2-thiouracil; 6-METHYL-2-THIOURACYLE; 6-(methylsulfanyl)pyrimidine-2,4(1H,3H)-dione; 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one

Molecular Formula：C5H6N2OS

Molecular Weight：142.1789

InChI：InChI=1/C5H6N2OS/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)

CAS Registry Number：56-04-2

EINECS：200-252-3

Density：1.36g/cm3

Boiling point：342.3 deg C at 760 mmHg

Refractive index: 1.638

Flash point: 160.8 deg C

Vapour Pressure: 3.83E-05mmHg at 25 deg C

Methylthiouracil is an antithyroid preparation. It is a thioamide, closely related to propylthiouracil.

Methylthiouracil is not used clinically in the United States, it has a similar mechanism of action and side effect to that of propylthiouricil.

The drug acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland.

The clinical effects of the drug to treat the hyperthyroid state can have a lag period of up to two weeks, depending on the stores of thyroglobulin and other factors.