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Chlorogenic Acid Extract Powder Eucommia Extract Powder

 

Description Of Eucommia Extract Pure Chlorogenic Acid

 

Eucommia Ulmoides P.E./ Eucommia Leaf Extract/Chlorogenic acid

 

Botanical Name: Eucommia Ulmoids Oliv.

 

Part Used: Leaf , Bark

 

Active Ingredient: Chlorogenic Acid

 

CAS No.: 327-97-9

 

Molecular Formula : C16H18O9

 

Structural formula:

 

Specification

 

Extract Ratio 4:1 5:1 10:1 20:1 50:1 100:1 200:1

 

20% Chlorogenic Acid, 25% Chlorogenic Acid, 30% Chlorogenic Acid, 50% Chlorogenic Acid,

 

90% Chlorogenic Acid,98% Chlorogenic Acid

 

1. Sources and Composition of Eucommia Leaf Extract Chlorogenic acid

1.1. Sources

More commonly referred to as the Gutta-Percha or Rubber Bark tree or the Traditional

Chinese Medicine known as Du Zhong, Eucommia ulmoides (of the Eucommiaceae family)

is a medicinal plant where both the leaves and the bark have been used for the purposes of

hastening relief of back pain, to increase stamina and recover from fatigue, and to make

bones and muscles stronger[1] while promoting longevity and fertility.[2] When used in

Kampo medicine, it goes by the name of Tochu[3] and the leaves are sometimes used to

brew Tochu tea.

This plant also has some usage as a tree that can produce rubber[4] due to the trans-

polyisoprene compounds it can produce,[5][6] which is why the tree also has the common

name of 'Rubber Bark Tree'.

Eucommia ulmoides is a medicinal plant recommended to support vitality and strength,

and also has commercial benefits as the tree can be used to manufacture rubber

1.2. Composition

The bark (ethanolic extract unless otherwise stated) has been noted to include:

Geniposidic acid (0.925% of bark) and its aglycone geniposide (0.488%) and genipin

(0.214%)[7]Trans-polyisoprene compounds, used mostly in rubber making[6]

Lignans (+)-pinoresinol-4,4′-di-O-β-D-glucopyranoside (pinoresinol diglucoside[8]), (+)-

pinoresinol-4-O-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside, (+)-me esinol-4,4′-di-

O-β-D-glucopyranoside, (+)-syringaresinol-4,4′-di-O- β-D-glucopyranoside, (−)-olivil-4′-O-

β-D-glucopyranoside, (−)-olivil-4-O-β-D- glucopyranoside, and (+)-pinoresinol-4-O-β-D-

glucopyranoside[9] with both syringaresinol diglycoside (0.214%) and (+)-pinoresinol-di-

β-d-glucopyranoside (0.991%) being quantified[7]Licoagroside F (28.78+/-0.81μg/g)[10]

The flavonoids Baicalein (0.28+/-0.010μg/g), wogonin (0.20+/-0.0027μg/g), and oroxylin A

(0.09+/-0.0040μg/g)[10]

Caprylic acid (involved in androgen signalling[1] and also found in Coconut Oil)

Triterpenoids[1]

Chlorogenic acid (0.302%)[7]

Whereas the leaves of Eucommia ulmoides include:

The irioid glycosides Geniposidic acid (10.1-17.4mg/g),[11][12] Aucubin (6.5-19.7mg/g;

geniposidic acid without the carboxylic acid group),[12][13] and Asperuloside (13.7-27.8mg/g)

[14][15]

Quercetin (0.27-0.62mg/g) as isoquercetin, rutin (7.6-14.3mg/g), and 3-O-sambubioside[11]

[12] as well as 3-O-alpha-L-arabinopyranosyl-(1->2)-beta-D-glucopyranoside[16]

Kaempferol and astragalin (kaempferol 3-O-beta-D-glucopyranoside)[16]

Licoagroside F at 8.97+/-0.41μg/g[10]

Baicalein (0.23+/-0.002μg/g), Wogonin (0.19+/-0.0030μg/g), and Oroxylin A (0.04+/-0.000

4μg/g)[10]

Lignans Syringaresinol di-O-Glc (275.53+/-0.99μg/g) and Pinoresinol di-O-Glc (384.15+/-

19.67μg/g)[10]

Chlorogenic Acid (26.3-46.9mg/g)[11][12][17]

Ferulic and caffeic acid[11]

 

Product Name	Eucommia Ulmoides Extract Pure Chlorogenic Acid
Supplier	Hunan World Well-being Bio-Tech Co.,Ltd
Latin Name	Eucommia Ulmoides Oliv.	Family	Eucommia Ulmoides
Part Used	Leaves	Active Ingredients	Chlorogenic Acid
Specs Available	20% 25% 30%50%90%98%	Appearance	Brown yellow fine powder
Application	Pure Chlorogenic Acid,Pure Chlorogenic Acid,Pure Chlorogenic Acid 1).Eucommia Extract Chlorogenic Acid are applied in anti-hypertensive effect  2). Eucommia Extract Chlorogenic Acid are applied in anti-tumor effect 3). Eucommia Extract Chlorogenic Acid are applied in kidney, and  enhance immune function  4). Eucommia Extract Chlorogenic Acid are applied in anti-oxidation,  anti-aging, anti-aging musculoskeletal 5).Eucommia Extract Chlorogenic Acid are applied in anti-bacterial,  anti-virus  6).Eucommia Extract  Chlorogenic Acid also have other functions: diuretic,choleretic,lowering blood pressure, miscarriage.
Our advantage	Pure Chlorogenic Acid,Pure Chlorogenic Acid,Pure Chlorogenic Acid 1. We have our own factory, the quality can be controlled very strictly. 2. Our certification: HALAL,GMP,KOSHER,FDA,ISO22000,ISO14000. 3. Our Purpose: Provide you best quality, best service, best delivery.
Contact information	Pure Chlorogenic Acid,Pure Chlorogenic Acid,Pure Chlorogenic Acid Hunan World Well-being Bio-Tech CO.,Ltd Cherry Chan Tel:13501541862 Skype: qiurongchan Email: worldwellbeing02(at)gmail.com

 

What is Eucommia Ulmoides?

Eucommia is mainly grown in temperate regions of Asia mostly in China such as Guizhou, 

Sichuan, Hunan. The medicinal use of Eucommia ulmoides dates back to ancient Traditional 

Medicinal Chinese (TCM) including the texts of Yellow Emperor’s Internal Classic (Huangdi 

Neijing) (475221BC) . It has been used classically as a combination with other medicinal 

herbs or as a single agent to treat lower back pain and knees and strengthening the tendons 

and bones. In addition, it has also been used for prevention of miscarriage In modern medicine, 

majority of the preliminary data lend support to its use in osteoporosis, arthritis, hypertension 

with purported actions such as anti-oxidant and anti-nflammatory properties. From the long 

historical usage of over 2000 years and numerous preclinical and clinical studies, Eucommia 

ulmoides proves to be safe and non-toxic.However, there is no substantial evidence on its u

se during pregnancy, lactation and childhood.

 

What is 5~98% Eucommia Extract Powder/ Pure Chlorogenic acid?

Chlorogenic acids are cholegogues; their regular ingestion helps the flow of bile and thus

reduces the adverse effects of bile stagnation. Chlorogenic acids (see basic structure,

below) are found in all higher plants and are understood to have a role in the plant's

response to stress, particularly to damage such as breaking of leaves and flowers or

nicking the skin of fruits (1). The quantities present in most plants are miniscule, and thus

they do not play an important part in human diet or herbal medicines. However, a few plants

accumulate chlorogenic acids in quantities sufficient to have a physiological effect. The

primary dietary source of chlorogenic acid is coffee; the green coffee beans typically

contain 6-7% of this component (range: 4-10%); roasted coffee beans contain somewhat

less, as the roasting transforms chlorogenic acids into other molecules, which may still

retain the same functions.

 

Application Of Eucommia Extract Powder Pure Chlorogenic Acid

1).Eucommia Extract Chlorogenic Acid are applied in anti-hypertensive effect 

2). Eucommia Extract Chlorogenic Acid are applied in anti-tumor effect

3). Eucommia Extract Chlorogenic Acid are applied in kidney, and enhance immune function 

4). Eucommia Extract Chlorogenic Acid are applied in anti-oxidation, anti-aging, anti-aging 

musculoskeletal

5).Eucommia Extract Chlorogenic Acid are applied in anti-bacterial, anti-virus 

6).Eucommia Extract  Chlorogenic Acid also have other functions:diuretic,choleretic,lowering

blood pressure, miscarriage.

 

Main Functions Eucommia Extract Powder Pure Chlorogenic Acid

1. Eucommia Extract Powder has antihypertensive effects: Chlorogenic acid has significant 

antihypertensive effect, which is smooth, and non-toxic without side effects.

2. Eucommia Extract Powder Chlorogenic Acid as anti-tumor effects: Modern 

pharmacological experiments show that chlorogenic acid has the effects of anti-cancer 

and tumor suppressor.

3. Eucommia Extract Powder  Chlorogenic Acid has the effects of strengthening Kidney and 

enhancing immune function: experimental results show that chlorogenic acid can excite 

pituitary and adrenal cortex system and can enhance the function of the adrenal cortex.

4. Eucommia Extract Powder Chlorogenic Acid is a antioxidant, anti-aging, against free

radicals, promoting metabolism

5.  Eucommia Extract Powder Chlorogenic acid has antibacterial, anti-inflammatory effects. 

It decreases blood pressure and increases white blood cells and gastric peristalsis and 

secretion significantly.

 

Health Benefits of Eucommia Extract Chlorogenic Acid

1. Anti oxidative effects of Eucommia Extract Chlorogenic Acid

In the investigation of the impact of consumption of a coffee containing high levels of

chlorogenic acids on the oxidation of proteins, DNA and membrane lipids; additionally,

other redox biomarkers were monitored in an intervention trial, found that the oxidation

of DNA, lipids and proteins associated with the incidence of various diseases and the

protection against their oxidative damage may be indicative for beneficial health effects

of coffee.

 

2. Hepatoprotective effects of Eucommia Extract Chlorogenic Acid

In the investigation of the potential protective effects of chlorogenic acid (CGA) on acute

liver injury caused by lipopolysaccharide (LPS) in mice, found that CGA also decreased the

elevated plasma levels of ALT and AST. At the transcriptional level, CGA pretreatment

suppressed hepatic mRNA expression of toll-like receptor 4 (TLR4), TNF-alpha and NF-

kappaB p65 subunit. In contrast, mRNA level of the transcriptional coactivator PGC-1alpha

was restored by CGA. Finally, CGA reduced the phosphorylation of NF-kappaB p65 subunit

in the liver.

 

3. Anti-obesity of Eucommia Extract Chlorogenic Acid

in the investigation of the efficacy of chlorogenic acid on altering body fat in high-fat diet

(37% calories from fat) induced-obese mice compared to caffeic acid. Caffeic acid or

chlorogenic acid was supplemented with high-fat diet at 0.02% (wt/wt) dose, found that

Caffeic acid and chlorogenic acid significantly inhibited fatty acid synthase, 3-hydroxy-3-

methylglutaryl CoA reductase and acyl-CoA:cholesterol acyltransferase activities, while

they increased fatty acid beta-oxidation activity and peroxisome proliferator-activated

receptors alpha expression in the liver compared to the high-fat group.

 

4. Anti-inflammatory effects of  Eucommia Extract Chlorogenic Acid

In the assessment in vivo of the anti-inflammatory and antinociceptive activities of the

aerial part and root extracts of Scorzonera acuminata, Scorzonera cana var. alpina,

Scorzonera cana var. jacquiniana, Scorzonera cana var. radicosa, Scorzonera cinerea,

Scorzonera eriophora, Scorzonera incisa, Scorzonera laciniata ssp. laciniata, Scorzonera

parviflora and Scorzonera sublanata and theirs effect against inflammation and to relieve

pain, found that Scorzonera cana var.

 

5. Antioxidants of Eucommia Extract Chlorogenic Acid

In the study of the chemical composition and the antioxidant activity of spent coffee

grounds and coffee husks extracts, obtained by supercritical fluid extraction (SFE) with

CO(2) and with CO(2) and co-solvent, found that the best antioxidant activity was showed

by coffee husk extracts obtained by LPE. The quantification and the identification of the

extracts were accomplished using HPLC analysis. The main compounds identified were

caffeine and chlorogenic acid for the supercritical extracts from coffee husks.

 

6. Antitussive of Eucommia Extract Chlorogenic Acid

In the investigation of the orally administrated the water extracts in mice. Ammonia

induced mice coughing model was used to evaluate the antitussive activity, found that

only flower bud can be used as the antitussive and expectorant herbal drug. The high

concentration of chlorogenic acid, 3,5-dicaffeoylquinic acid, rutin in flower buds may be

related with the antitussive and expectorant effects of Flos Farfara. To guarantee the

clinical effect, rachis should be picked out before use.

 

7. Rheumatoid Arthritis of Eucommia Extract Chlorogenic Acid

In the investigation the antiarthritic activities of this compound in adjuvant induced-arthritis

in male Wistar rats, and exploration of the underlying mechanisms of actions in view of

immunological responses, found that CGA efficiently suppressed CD80/86 but failed to

bring any changes in the CD28 count, whereas ibuprofen (standard drug) resulted in highly

significant inhibition of both.

 

Packing

Material: In fiber-drums with two-plastic bags inside.

Wight: net weight 25kg/drum; gross weight 28kg/drum

Drum Size & Volume: I.D.42cm × H52cm, 0.08 m³/ Drum

 

Shipping

<50kg by Express, delivery cost according to quantity you order.

50kg <goods<100kg by air, delivery cost is around $10/kg

100kg<goods<500kg by air, delivery cost is around $6-8/kg

goods>500kg by sea, delivery cost is very cheap.

 

Storage

Stored in a cool&dry well-closed container, keep away from moisture and strong light/heat.

   

How to make order & payment?

1 Proforma invoice will be sent after your confirmation of the order.

2 We can accept payment by T/T, Western Union, Escrow(Alibaba), paypal. 

Cherry Chan

Tel:13501541862

Skype: qiurongchan

Email: worldwellbeing02(at)gmail.com